Married five times to: Virginia Cherrill, Barbara Hutton, the Woolworth Dimestore Heiress, and Betsy Drake with whom he made two movies. This lasted the longest of his five marriages. His fourth wife, Dyan Cannon, was an actress also and they had one daughter, Jennifer Grant, his only child. His last wife was Barbara Harris.

Irene Dunne, who made three films with Cary Grant, stated that she had worked with many leading men, but working with Cary was different, he was much more fun. She goes on to say, "People usually react with skepticism when I say that Cary's intelligence and seriousness of approach were his strongest points as an actor, but this is true. Behind that carefree and sophisticated man on the screen, there's a painstaking worker and keen mind at work. When I acted with him he was too busy to really enjoy his stardom. He was a modest man who continually worked at his craft to show everyone that his popularity wasn't due to his looks -- even when such proof was no longer neccessary."*

"I will always remember two compliments he paid me. He said I had perfect timing in comedy and that I was the sweetest smelling actress he ever worked with."*

*Taken from Close-Ups, The Movie Star Book, article "Cary Grant: Working With A Man of Quality" by Irene Dunne, Page 386